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The effect of Iranian propolis on glucose metabolism, lipid profile, insulin resistance, renal function and inflammatory biomarkers in patients with type 2 diabetes mellitus: a randomized double blind clinical trial ECE2019 21st European Congress of Endoc
However, the serum HDL-C had significantly increased in the propolis group compared with the placebo group. There was also a significant decrease in serum liver transaminase ALT and AST and blood urea nitrogen BUN concentrations in the propolis group. Iranian propolis has beneficial effects on reducing post prandial blood glucose, serum insulin, insulin resistanc e, and inflammatory cytokines.
Biological Activities of Chinese Propolis and Brazilian Propolis on Streptozotocin-Induced Type 1 Diabetes Mellitus in Rats.
Brazilian propolis showed an obvious inhibitory effect on BUN level and both Chinese and Brazilian propolis decreased the UAER, ALT and AST levels. These results demonstrated the protection effect of propolis on hepatorenal function in diabetic rats. This conclusion was consistent with several previous reports, which showed that propolis and its active constituent caffeic acid phenethyl ester CAPE have apparent therapeutic effects on liver and kidney lesions in animal models 27 - 30.

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